The TB Portals Program Steering Committee is the central advisory body of the Program. It consists of representatives from each country participating in the Program and includes vast expertise in TB research, clinical medicine, and public health.

The Steering Committee provides feedback and guidance on new projects and overall TB Portals Program direction. Representatives serve as a key experts on TB in their respective countries. The Steering Committee meets as an entire group once a year to share achievements from the past year, discuss current issues and challenges, and decide on new research directions.